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Ecolab Life Sciences Launches New Bioprocessing Purification Resin to Drive Manufacturing Productivity

Purolite¢â AP+50 resin enables improved cost efficiencies in antibody manufacturing
´º½ºÀÏÀÚ: 2025-06-25

ST. PAUL, MINN. -- Ecolab Life Sciences today announced it has launched an innovative new resin to help achieve cost savings and optimize operations throughout the antibody manufacturing process. Purolite™ AP+50 is an affinity chromatography resin with a 50-micron bead size offering the highest dynamic binding capacity of the AP resin platform while providing excellent durability for monoclonal antibody capture. It also leverages Ecolab’s patented Jetted resin bead manufacturing technology, an innovative approach that enables lot-to-lot consistency and shorter lead times. It is the latest addition to Ecolab’s robust Purolite Resin affinity toolbox which helps biopharmaceutical companies and Contract Development and Manufacturing Organizations solve complex purification challenges.

“The ability to effectively improve process economics while maintaining purity is the gold standard of resin purification. As pharmaceutical and biotech companies seek to increase savings and improve business continuity, they are requiring innovative solutions to accelerate and de-risk manufacturing,” said Meeta Gulyani, senior vice president and general manager, Ecolab Bioprocessing. “Our resins are designed to help customers improve their product development platforms and implement next-generation manufacturing processes as well as enhance dual sourcing strategies that can reduce costs and bolster supply chains.”

Purolite AP+50 resin joins Ecolab’s full suite of purification resins including the recently launched Purolite DurA Cycle™ A50 for longer lifetimes and Purolite 70 CH1 which targets complex antibody fragments. Together, they support process intensification strategies and cost of goods reduction, which are critical in late-phase, large-scale manufacturing.

Ecolab’s newest innovation is being formally introduced at the 2025 BIO International Convention in Boston, Massachusetts from June 16 - 19, 2025. Attendees are invited to learn more about Purolite AP+50 resin at the Ecolab booth (#1971) and via a technical presentation at the BPI Theatre on Tuesday, June 17 at 2:40 p.m. EDT.

The announcement of Ecolab’s latest resin follows news of the opening of its newest Bioprocessing Applications Lab in King of Prussia, Pennsylvania. The new lab complements its UK-based facility, providing dual continent technical support capabilities, including resin screening and development applications to address growing customer demand around the world.



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